podcast

From First Principles

Krishna Choudhary and Lester Nare

From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it…

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What Happens When AI Gets a Lab? 2026-10-21 · 99m
Nobel Prize 2026: The Science Gets Stranger 2026-10-16 · 119m
Nobel Prize in Chemistry 2026 Explained: Mirror Molecules (EP 63) 2026-10-07 · 81m
Nobel Prize in Physics 2026 Explained: IceCube & Neutrinos (EP 62) 2026-10-06 · 62m
Nobel Prize in Medicine 2026 Explained: Optogenetics (EP 61) 2026-10-05 · 71m
2026 Nobel Prize Predictions: Medicine, Physics & Chemistry (EP 60) 2026-10-03 · 41m
Golden Goose Awards 2026: The Science Behind the Winners (Part 1) (EP 59) 2026-09-29 · 127m
What OpenAI Actually Did to Navier-Stokes (EP 58) 2026-09-24 · 249m
What’s Next in Science? Nobel Prizes, Space Missions & More (EP 57) 2026-09-14 · 64m
The Yak Mutation That Could Help Repair the Brain (EP 56) 2026-09-07 · 96m
Why Spin Qubits Will Win the Quantum Race (Part 2) (EP 55) 2026-08-31 · 226m
How Quantum Computing Actually Works (Part 1) (EP 54) 2026-08-20 · 131m
What Claude Actually Did to the Riemann Hypothesis (EP 53) 2026-08-14 · 107m
The Amazon’s Hidden Civilization (One Year Anniversary) (EP 52) 2026-08-06 · 107m
The Tech Elon Has Been Waiting For (EP 51) 2026-07-31 · 104m
AI Breaks a 90-Year Math Problem, Life’s Alphabet in Space, and Science Funding (EP 50) 2026-07-23 · 113m
FIFA Data Scientists Explain Match Momentum (EP 49) 2026-07-17 · 40m
Black Hole Movies, Digital Heart Twins, and World Cup Tech (EP 48) 2026-07-14 · 108m
America 250: The Breakthroughs That Built American Science — Part 2 (EP 47) 2026-07-03 · 141m
America 250: The Breakthroughs That Built American Science — Part 1 (EP 46) 2026-07-02 · 110m
The Physics of the World Cup: VAR, Smart Balls, and Soccer Aerodynamics (EP 45) 2026-06-29 · 60m
New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics) (EP 44) 2026-06-26 · 98m
Dr. Michael Blanton on Open Data, Galaxy Surveys, and the Future of Astronomy (EP 43) 2026-06-04 · 43m
How Scientists Actually Study Dark Matter (EP 42) 2026-05-21 · 67m
Dr. John Mulchaey on Carnegie Science and the Future of Astronomy (EP 41) 2026-05-13 · 37m
Ant Scans, Lunar Chickpeas, Hidden Galaxies & Superconductivity (EP 40) 2026-04-29 · 37m
The Prometheus Constellation: Dramaturgical and Scientific Analysis of the Physicists in Oppenheimer (EP 39) 2026-04-21 · 97m
Harder Than Diamond? The New Hexagonal Diamond Breakthrough (EP 38) 2026-04-15 · 58m
Artemis II: Deep Dive on the Moon Flyby, Earthset, and Reentry (EP 37) 2026-04-09 · 86m
Artemis II, Claude Code Leak, iPhone Spyware & Project Hail Mary (EP 36) 2026-04-03 · 61m
Can AI Help Wake Coma Patients? The Science of Consciousness (EP 35) 2026-03-31 · 69m
AI Cancer Vaccines, Strange Fish, Ketamine, and Ancient Life (EP. 34) 2026-03-27 · 45m
Can Human Neurons Really Play Doom? The Science Behind Wetware (EP. 33) 2026-03-24 · 73m
5,000-Year-Old Bacteria, Solar Storms, Dogs, and Meta’s AI War (EP. 32) 2026-03-20 · 39m
Optovolution: Teaching Proteins to Think Like Computers (EP. 31) 2026-03-18 · 56m
Can We Stop an Asteroid? The Physics Behind NASA’s DART Mission (EP. 30) 2026-03-16 · 54m
Astrobiology’s Biggest Survival Test + A Vaccine Against Everything? (EP. 29) 2026-03-12 · 124m
Dark Galaxies, Fuzzy Dark Matter, and an Alzheimer’s Breakthrough (EP. 28) 2026-03-04 · 112m
Dream Engineering, the Proton Radius Puzzle, and an ALS Breakthrough (EP. 27) 2026-02-26 · 132m
Winter Olympics Deep Dive: Ice Physics, Performance Pressure, and Climate Change (EP. 26) 2026-02-18 · 110m
Plants, Quantum Sensors, and Predicting Cancer Evolution (EP. 25) 2026-02-10 · 109m
Artemis II, Apollo, and the Physics of Going Back to the Moon (EP. 24) 2026-02-04 · 70m
JWST’s “Little Red Dots,” TimeVaults, and the Dawn of Math (EP. 23) 2026-01-27 · 101m
Cloud9 Dark Matter Halo, Jellyfish Sleep, and String Theory Hidden in Nature (EP. 22) 2026-01-20 · 100m
Roman Concrete, Brain “Cognitive Legos,” DeepSeek, and Econophysics (EP. 21) 2026-01-12 · 119m
The Physics Behind Fusion’s Biggest Problem (Season Finale) (EP. 20) 2025-12-23 · 78m
The Race to the Double Helix — Watson, Crick, Franklin & the Real Story of DNA (EP. 19) 2025-12-04 · 94m
3I/ATLAS Explained, Forensic Fingerprints & Alzheimer’s Breakthrough (EP. 18) 2025-11-27 · 88m
Hypersonic Physics, Deep Sea Life & Princeton’s Millisecond Qubits (EP. 17) 2025-11-22 · 93m
Octopus Camouflage, Orcas vs. Sharks, Civet Coffee & Sub-Diffraction Telescope Tech (EP. 16) 2025-11-13 · 78m
AI-Generated Genomes, Retinal Implants, and Palomar’s Mystery Lights Explained (EP. 15) 2025-11-06 · 124m
Chen Ning Yang — The Man Who Unlocked Symmetry (EP. 14) 2025-10-31 · 103m
Portable Muon Beams, Sodium Batteries, and the Secret to Long Life (EP. 13) 2025-10-23 · 96m
From Princeton to the Nobel Prizes — How FFP Started + 2025 Nobel Recap (EP. 12) 2025-10-15 · 72m
From Cells to Circuits to Crystals — 2025 Nobel Prizes Unpacked (EP. 11) 2025-10-09 · 114m
AI Supercharges CRISPR & LIGO (Nobel Prize Week Preview) (EP. 10) 2025-10-02 · 156m
China’s AI Breakthrough, Time Crystals, Hidden Viruses, & Brightest Cosmic Signal (EP. 9) 2025-09-23 · 102m
Strongest Evidence for Alien Life? (Mars, K2-18b & JWST) (EP. 8) 2025-09-16 · 80m
Interstellar Visitor 3I/Atlas, Human Longevity Plateau, New No-Sort Plastic & Analog AI (EP. 7) 2025-09-09 · 84m
New Supernova, Virus+Bacteria vs Cancer, Electron Spin, Bee Superfood (EP. 6) 2025-09-02 · 88m
Hacking The Human Brain, Unlocking Our DNA, Unbreakable Diamonds & The Quantum Magician (EP. 5) 2025-08-26 · 130m
3rd Interstellar Visitor, Rubin’s Sky Camera, AI CRISPR Boost & T. rex Blood Vessels (EP. 4) 2025-08-19 · 82m
Oldest Molecule, Programmable Proteins, Europa Radar & Light’s Double Life (EP. 3) 2025-08-14 · 77m
Hidden Star in Betelgeuse, Dancing Atoms, Ultra-High-Energy Cosmic Rays & VR Immunity (EP. 2) 2025-08-05 · 78m
Earth’s 1-ms Day, Baby Solar Systems, Record Black Hole Crash, CRISPR Cancer Hack & AI Indiana Jones (EP. 1) 2025-08-01 · 56m
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From First Principles

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