Insulin Doctor: This Is The First Sign Of Dementia! The Shocking Link Between Keto & Brain Decline!

0:00 Welcome to the sardine challenge. So the only thing on the menu for the next three days is sardines. I challenge you to try and eat three of those cans in a day because that's a hell of a tool to help you get into a ketogenic state. And when you're in a ketogenic state, it helps burn fat. Muscle mass gets higher preserved. I've seen patients that have reversed their gray hair, embed brain performance, concentration, and energy, all of those things improve. And so I'm gonna teach you how to do an advanced ketogenic diet. Good luck in that off. Dr. Annette Bosworth is the insulin resistant specialist. With over two decades of experience, she's discovered that the key to your health isn't more treatments. It's to get into a ketogenic state. Most people have been making buckets of insulin without knowing it. But when you have excess insulin, it's a chronic disease maker. It is what makes high blood pressure. It is what makes cancer. It is what makes debris in the brain, which is linked to depression, rain fog, Alzheimer's, and Parkinson's. And so to reverse the high insulin state, I really push my patients to do the ketogenic diet and what Unfolds is your best life ahead within a year. Like I really rescued my mom from the edge of death.

1:06 So where do I start? First thing is quit eating till late at night because you're stimulating an excessive production of insulin. The next thing keep the carbs low, put the fat up, more eggs, beef brisket, ribs, pork belly. But then people often say when you talk about the ketogenic diet that it's not sustainable. So you have this idea of this keto continuum. Consistently keto for life. Yeah. I mean I've been on a ketogenic diet for ten years. There's twelve steps for it. And you're not gonna have to try very hard. So the first step is Just give me thirty seconds of your time.

1:35 Two things I wanted to say. The first thing is a huge thank you for listening and tuning into the show week after week. It means the world to all of us, and this really is a dream that we absolutely never had and couldn't have imagined getting to this place. But secondly, it's a dream where we feel like we're only just getting started. And if you enjoy what we do here. Please join the twenty four percent of people that listen to this podcast regularly and follow us on this app. Here's a promise I'm gonna make to you. I'm gonna do everything in my power to make this show as good as I can now and into the future. We're gonna deliver the guest that you want me to speak to, and we're gonna continue to keep doing all of the things you love about this show.

2:12 Thank you. Doctor Annette. Bosworth. Or shall I call you Doctor Buzz?

2:21 What is it that you know and believe and understand that you think the general public doesn't know, believe and understand. Mm. That most of the reasons people come to see me Could be reversed.

2:34 If they knew how to make ketones on a regular basis. So I'm an internist. Uh that means uh if you go to an internal medicine doctor and we don't know what's wrong. You're gonna die. We take care of tough puzzles and we do this over a long

2:48 Management, chronic disease management. So I've got twenty five years of studying chronic problems that Deteriorate the quality of life. Life span, health span both go in the toilet when you're chronically seeing me.

3:02 And you could Abort all of that. Destiny. If routinely you were making ketones. An intern, it sounds like an intern. I'm trying to understand the terrible. The marketing on this is terrible. It just means you're supposed to take care of a very complex answers. Your job

3:18 I mean, the buck stops with you. If if the internal medicine team can't figure it out You're gonna die. So you so you're basically a chronic illness doctor. Chronic disease management is absolutely it. You know, I love the way uh Peter Atia uses medicine two point oh, which is what we are the masters of, managing it, making sure the prescriptions are there, making sure you are treating all these problems. The internist being one of your best buddies,'cause you're having to see them routinely. You gotta get the meds refilled, you gotta check for the side effects. It's a mill.

3:46 What is medicine two point oh in your definition? Yeah, so I can keep you from dying from childbirth and infections, and I have an antidote for every one of your symptoms. We are in a world where medicine has answered a lot of problems. Little things like high blood pressure, little things like it's a few extra pounds around the middle, little things like Brain fog. Oh my eyes are aging. All of these are signals that Your body has made more trash than it cleaned up.

4:13 And there were some rules to humans. That you missed. And for for my listeners that have clicked on this conversation. What are they gonna get out of here? Giving us that time.

4:24 And staying with us and listening to this. What is the end goal gonna be for them in their lives? I talk to my patients and teach them the steps. How to reverse the medical problems. That you've already got on the roster. And by doing that.

4:38 The freedom. Is to be the kind of grandparent. That you dreamt of. But you've surrendered can't be there anymore. And what is the list of predicaments or illnesses that

4:49 Yeah. Most common one is being overweight and a brain that's not working right. What really is behind all of the patients I've seen for twenty five years is Or working on peak brain performance. Even if you don't think about that, that's what I think about. So when you come in and you're fifty five years old and I can see the worry of Parkinson's headed your way.

5:09 super young is fifty five years old with Parkinson's. That is a brain. It's got too much trash. And you don't know it yet. And I mean in the history of Doctor Boss versus Parkinson's Parkinson's has like three thousand five hundred patients. I have zero. Parkinson's wins every time. And the the biggest moment of people who have chronic problems under the hood.

5:31 Is they have no idea. That it's coming. And once that lands The reversal is much worse. Seeing it ten years before it's supposed to be there.

5:40 This is a gift saying, Let me show you how to undo that. Back away from the edge. It's that brain function that you're going to miss the most. When it doesn't work. And it's linked to all of these things like the arthritis, the you know, weight around the middle, the high blood pressure, the severe uh connection to mental. uh approach, meaning you can say depression, but people say, Oh, I don't have that diagnosis. I'm talking about a brain that doesn't want to engage, that doesn't find joy in their life anymore, because

6:09 It's been too many years since they took out the trash. Let me show you how to take out the trash. And you're gonna have to do it a few times. But what Unfold.

6:17 Is your best life ahead within a year. So you're gonna teach me how to take out the trash? Yeah. To trash your own brain. Yep. And if I take out the trash of my own brain, how's my life gonna be better? You live in the twenty first century where there's lots of processed foods and lots of ways that your body did things without telling you.

6:33 So any injury that you've had, like a joint injury that keeps coming back every time you injure it It is a little easier to injure the next time. Is there a ring around the middle that's more More than pinch an inch? Is there a uh

6:48 distance uh uh in time where you say I can focus for this many hours, but I can't do it for this many hours anymore. Those are all places where If you did this, if you were able to say Don't stop taking out the trash several times a year. Several Times a month, if you ask me.

7:04 Then you never have to come into this World that's not. I just see people they're they're in quicksand. Up to their waist. In getting them out, they need a real lifeline.

7:14 And what are the current solutions people are typically offered when they're feeling yeah all the The ways that you described there, where they just don't feel good, they have brain fog, they're They might have chronic pain setting in in various ways. What are the typical solutions that medicine two point oh would offer them? Yeah, especially if they have good insurance. Yeah.

7:32 covered insurance plan and he's gonna say, Tell me the symptoms. I have a match game. I will give you the drugs that will Take away that one and take away that one and take away that one. What

7:43 Is always a Downside is well play that forward for ten years. Play it forward for five years. And d are the symptoms gone? No, but it will bridge and hold up the architecture of the body and the human. without actually fixing the problem, without actually diving in and say You got some chemistry problems.

8:00 Under the hood. that you don't measure and you don't talk about. But if you did. Even if you're not perfect, even if you're seventy percent You're gonna find yourself

8:10 At the age of fifty four. With Vitality and energy and sleeping through the night and not having what every other fifty four year old, which is chronic joint pain, a brain that can only focus for three to four hours without a break, uh, a stamina of uh endurance and health and Enjoy. That falls apart.

8:29 So when I'm you're fifty four years old. When I'm fifty four years old I wanna be as Young and energetic and articulate. and cognitively astute as you are. So what should I be doing now?

8:44 Don't decline, decay. In all those areas I described. Oh, what'd you have for breakfast? Today. Yeah. Um, I have not eaten breakfast yet. Okay, that's not a bad thing, but uh when you're fifty four

8:56 You should probably put the calories in the morning, not at night. We know that as you age The cost of a calorie. turns into timing. If you eat that fo one bite of food after six o'clock.

9:10 Is worth ten bites of food before noon. So if you're trying to say how do I get the best out of the nourishment but also Eating's fun. If you only get one bite after six o'clock and ten before. Move that food towards morning. When you're your age, uh what'd you have for what's the last meal you ate?

9:28 Yesterday. Yeah. Uh for dinner. I had This card. And I had salad.

9:35 I also had pasta. Okay. But I ate pretty late, which is a bad thing. What did you have the rest of the day before that? Just a big salad. Was that more towards n lunch or noon or Probably about four o'clock.

9:47 So it waited all the way till four o'clock to eat. Very common. This is a really common pattern of people doing what we would say intermittent or time restricted eating. They put that eating window in this, but it's got that balloon at the end of the day. Yeah. And it really does I mean what you're stimulating is an excessive production of insulin. And you're gonna wake up the next morning. What time did you wake up this morning? Today. Mm-hmm. I went to bed fairly relatively early for me. I woke up at about seven thirty AM. Oh. Usually it's later. And do you have did you have a solid seven, eight hours of sleep, or how? Yeah. So during that time, uh you finish eating around ten o'clock then it sounds like? Yeah. Okay, so then it's seven. Okay, so eleven o'clock and you've got uh seven seven thirty in the morning is when you woke up. So that's about eight hours since you've eaten.

10:33 Your insulin is still churning. Especially if the meal was large and there was carbs in it. So now you've got these processed foods late at night, and you're at the beginning of the disease, right? You're at the beginning of the chronic inflammatory. You don't do that.

10:49 You don't have high insulin throughout the night. So can you explain to me like I'm a twelve. What insulin is and the role it's playing.'Cause you know, I guess we're focused here on How to

11:00 I guess longevity, aging. Yeah, for a second. But how does insulin play a role in all of this and what is insulin? So Insulin Insulates. Okay, so think of it as it makes you fluffy. It makes you it puts the fat on.

11:13 Uh It's got some other roles too, but we're gonna talk about chronic diseases here, where it's not a scarcity problem. You you make plenty of it. And when it's in excess, it will store. Energy for when you go through a famine. It will also

11:29 Cause you to grow. Grow means g get a little fatter, but it also means things like their skin gets a little thicker, they have skin tags. And what I always think about is what's going on in their brain. And when that insulin is high for years and years and years

11:45 Uh, just like yours, because if if you didn't eat the rest of today. And then you got up tomorrow morning. It would be about that long after a late meal. Last night That's how long it would take you to say

11:58 Okay, we're back down to where we started from or where we should be in the morning. For someone that's never heard the word insulin before. there's some context to give on in terms of what it's doing. So it's coming out like a Transporter and helping put away the sugar will deal with the excess sugar. Right. So it it is what lifts yeah, it lifts glucose or sugar from the circulation. Into a cell. That's its first primary job.

12:19 But if all the cells are. Their storage is full. It's gonna start to pack it into the liver. I mean, let's say all those sort stores are full too. This job of the of insulin this hormon. Oozes into every part of your body.

12:33 To say make sure it's got full fuel, make sure it's got that sugar. But most people are Like What I would guess you are. Most of the time you don't you aren't a shortage of sugar. And so it feels it tops things off.

12:45 And then it will turn things into fat. It's too much sugar, they can't store it, all the storage is full. So you can send the signal out. Make me some more cells. I need some more storage units. This guy's eating more than he thinks he is. And we're gonna be prepared. The famine. Mm-hmm.

13:02 But in the meantime, turn it into fat. Make him a little fluffier. Is that the only consequence? Then I'm gonna I might be a bit more fat.

13:10 No, that's just the one people hear about the most. When you look at chronic disease management. Із the growth. Of Of the diseases of the inflammation, it's the making of the trash. So I keep saying, you know, you need to take the trash out f routinely.

13:24 Which mins That insulin, which has been smouldering higher than you think it is. because you live in today's world, because you eat processed food, because you eat super late at night. Uh you don't go two to three days without eating. You've you've got storage filled in your body. The high insulin levels in a healthy person.

13:41 Hides. That the debris is being made and you don't know it. Yeah. Yeah. Uh it's gonna put it in between two cells in your brain. It's gonna put it in between the skin cells. The trash doesn't get taken out until the

13:55 Insulin gets lower. And unfortunately Most people Have been making buckets of insulin without knowing it. Why?

14:04 What are they doing to create buckets of insulin? All the things you said about it. Um foods that come from boxes and barcodes and uh bags instead of whole foods instead A fat forward diet, which would then push that body into Making ketones. So

14:22 You can't you cannot make a ketone. If your insulin's high. Are there any signs that I might have high levels of insulin or insulin resistance. Abdominal girth is the first thing that is the first place that the fat goes.

14:36 So you do this really great part where you don't eat until later in the day. Mm-hmm. How does that feel during the day? During the day I feel really focused. I actually don't even know that I'm not eating. So that's really good. So what I would love to know is show me what your blood sugars are doing during the day. And show me if you make ketones. The answer is You

14:54 When you have excess insulin. Which is this Mm. Chronic disease maker. Uh, it is what makes cancer, it is what makes high blood pressure, it is what makes debris in the brain where

15:05 Call it depression or brain fog or Parkinson's. It's the Aging of the brain. It's linked to all of those things. All of those things. And that excess insulin nobody tells you about. But the symptoms are Dang, I feel like I gotta eat every two to three hours. Uh their debris

15:21 Yeah, or their fuel keeps running out. When you say Moi, I can eat. Uh once at the end of the day, and I'm pretty good. My focus stays really good. What I want you to prove is What are your ketones during the day?

15:33 So When When you've got a patient who has done that. Their ketones will be point seven. One point oh.

15:41 And They're taking out the trash all day long. So there's these two energy sources, one of them's the glucose, one of them's which is from like You know, eating pasta, which I ate last night. Um, so that probably put a lot of glucose in my bed. I probably had a high glucose spike and then insulin came out to deal with that.

15:56 And then there's keetones which start to appear when I'm fasting or when I haven't been eating carbs for a while and my body's looking for an energy source. Yeah. In terms of these two Energy sources. There seems to be a lot of hype around keetones. Mm-hmm.

16:12 So Why doesn't our body just run off ketones? It will as soon as you're done. Lowering your insulin. En I insulin grew.

16:20 In these patients. They didn't know that it was growing high. They went to their blood test and their glucose looked normal. What nobody checked for years is how much of that insulating hormone did it take to keep the glucose controlled. And that's where chronic diseases are are grown in spades. That's where autoimmune disorder. Yes. Okay. So that excess insulin for the last

16:41 Decade. had you come into my clinic, we'll put a label on it, f call it PCOS, call it in uh high blood pressure, call it Um autoimmune problems. All of them are linked to high insulin. Glucose, when you want to store it.

16:55 We put it in a fancy string called glycogen. And it's just an efficient way to store glucose, but as soon as your body needs it, it will unlock all that sugar back into your access, back for you. What you don't realize is Well, how much glycogen got you got stored over there? How much is there in storage?

17:13 And that is what high insulin has been doing. Just put it in storage, put it in storage. And then When you stop eating You'll know if you emptied out all your stored sugar, which is Some of the regular sugar you just ate, but then all this glycogen, this packaged sugar.

17:28 How empty are you? I don't know. Have you made a ketone yet? You cannot make a ketone, you cannot burn fat until that. That tank is empty. Okay, so I have these glycogen stores which last for what, a day or two? Oh no. Think of it as brown sugar.

17:44 So you package the sugar really tight. Then you put it in the back of the drawer and it turned crusty. 'Cause you never lowered your insulin. I have patients that are over overweight and we put them on a ketogenic we put them on a twenty total carbohydrates per day. So super low carbohydrate. It is.

17:59 fifteen days before they make a ketone. Okay. So it's it could be a a one it could be up to two weeks, for example. Right. Before my glycogen stores are empty. And it's not until my glycogen stores, my glucose stores are empty, that my body can start producing ketones. Correct. So it's gonna exhaust all of those glycogen stores. And then once it's run out, it's gonna switch into this keych state. Right. Yeah. Think of it as

18:22 Your short term Easy to access, sugar. Has to decrease. And that means your insulin has decreased. That hormone for insulate. They both run in tangents. You decrete your emptying glycogen, your insulin's going down. So how do I know if I have

18:38 Insulin. Resistance. What what are the key signs? You mentioned skin tags. I've never had that time before. Yeah, skin tags are not moles. So moles you can feel this bump on your on your skin, right? But a skin tag has a neck. And like a little mushroom.

18:52 And It's the most annoying thing when patients come and say, Well, I just tried to cut'em all off, but they kept bleeding. Like Do not cut them off. When your insulin's lower.

19:03 So that's the first place. It'll be found in their armpits or places where their skin rubs. So armpits and they're growing. And once insulin starts to grow them, it's like a crop. A crop of little baby cauliflower hanging out in their armpits. You talked about velvety skin as well being an a an indicator. Velvety skin is this Latin word acanthosis nigger cans, which is fancy word that means the skin is darker and thicker. So the The places it usually happens is the back of the neck.

19:30 And you'll hear You know, stories of I tried to wash my neck. It's it's dirty all the time. It's not dirt. It is the way the skin is under the the curse of high insulin. And you see it in teenagers all the time now. They put on weight and their growth hormones are already doing that teenage thing. Now you put high insulin in there.

19:51 And they have this dirty neck syndrome, or on the creases of their elbow. It's just darker here. That is pathology, that's not normal. From high insulin. You talked about weight changes as well. W what's this thing about hairy toes that I was reading about? Right. So as my patients age, so most of my fifty five year olds that have had high insulin. I will tell them, look at your toes.

20:13 They're supposed to have hair on them. And when your body has had that high insulin state for a couple of decades now. It will start to say We don't send resources to a couple parts of the body anymore. And the follicles in their toe?

20:28 or one of them. Like just stop growing hair on your toes. And there's an ascending problem with this where the toe starts, then it's the ankles, then it's up to the knees, and they don't have hair anywhere on their lower extremities. Із а просес. But started from high insulin. What about aging? You talked about how If you have I high insulin, there'll be an impact on your aging. Now I'm thinking about, you know, I'm getting a couple gray hairs down this is because of my insulin levels. I I have seen patients w that have reversed their gray hair on a ketogenic diet. It blew my mind. They asked me for the reason why that happened, and I thought

21:01 Well Um the cell are healthier that are making your hair. That's all I got. Um aging is exactly that Enemy. Which is

21:11 They are Going around the sun with more growing of the trash than they needed. So that high insulin, they don't know about it, they've not produced a ketone in years. And that chronic disease is now

21:24 difficult to get their The eye to clean out. It's difficult to get that Brain Trash removed. And you're supposed to do it every night when you sleep.

21:33 It's not supposed to be behind this far. You're two decades. From taking out the trash in your brain. That's aging. How do I

21:41 First start even know my ketone blood levels. Well when when a patient first comes in saying, How do I begin? I want them to tell me what they had for their meal and then say, How many carbs do you think that was? because this education like an apple

21:56 Is twenty grams of carbs, fifteen grams of carbs for some of them. And we're gonna ask you in the first six weeks to take your carb intake down to less than twenty. Twenty total grams of carbohydrates or less is where we begin. And again, I do this in a medical grade. There are people who play with a ketogenic diet and there's people who try to reverse medical problems with a ketogenic diet. In order to do this.

22:18 It is not a lazy kind of keto. You have to actually be on the same team as me using data to reverse this medical problem. And how how does it One measure. Yeah. I I think blood is the best. There is a way you can measure them in a in urine. The Burning of fat if you

22:37 Turn that. String of fat into ketones. There are two destinies for that. You either put it into a mitochondria and turn it into energy. Or you pee it out. So especially when they're early in a ketogenic journey.

22:49 They're they overshoot. Evolution said, Don't let them die. Turn that fat into energy. help them through the famine. So the excess

22:58 Keetones they make. End up in their urine. We call them P tone strips. And they're cheap and easy and We don't have to cross that barrier of somebody pricking their finger at the beginning.

23:07 So they're gonna pee out ketones every day. As long as they're not Chronic. Insulin resistant. So if I avoid carbs for a con sustained a period of time, which could be a couple of days, it could be up to two weeks. Eventually my body's gonna say, Listen, we need energy. So so it's gonna start burning my fat stores. Yes. You know, from some of that

23:28 Fat around the mid section and it's gonna start turning that into ketones. Which are A different type of energy. Are there any reasons why ketone as a source of energy is better for me in terms of performance.

23:42 Other than the insulin reasons that we've talked about. Like are there any other parts of my body or my health that benefit So ketones. For starters, when you're burning a ketone, there's less trash. Okay, it is a cleaner

23:54 uh fuel with less byproduct, especially as you age. So you get the longer energy and you have less debris floating around. You hear the word antioxidants all the time. Well Burning ketones is an antioxidant state. It is a And it's in the space where you need it, which is inside that cell. How you swallow antioxidants and you have no guarantee that they end up where they're supposed to. So number one, the fuel.

24:19 Is Reducing trash at a cellular level. It lasts longer and it penetrates through that blood brain barrier. To fuel a brain that

24:30 Even if it's insulin resistant. It can use a ketone. So the problem with somebody who's chronic Insulin resistance. Their brain needs a lot of glucose to stay on online. And

24:43 I can try to get it there. But insulin is constantly fighting that. It's a war. To try and keep the glucose in their brain. My hack is

24:51 Ketones will go right around that. It doesn't need the same transporters to get across the blood brain barrier, and especially to fuel those cells in the brain. So for performance, Um, I mean name a game where you don't use your brain. There isn't one, right? You're you're gonna if you're looking at performance to say, let's begin with the sharpest brains and the most focus, the most discipline, the less Um impulsivity. all of those things improve when that brain is being fueled with ketones.

25:19 So let's focus on the brain part then. So What have you personally noticed as someone Who I assume is in the ketogenic diet right now. Yes. What have you noticed the variances between when you're in a keto diet and when you're not? Right, well, I've been doing this since twenty fifteen. So um the onset of it was really messy, but uh the seasons where I would do a great job.

25:40 And then I would think I'm fine. Uh I I mean I can tell you you see twenty five patients in a day. And I feel bad for the last five. Uh they've got a they've got a sluggish brain. I don't care how much coffee you've got in you, you can't keep that focus for that

25:55 Yeah. Um when you're in a ketogenic state and not in a ketogenic state, uh the f the the brain power, the concentration, the ability to Keep your mood controlled. Is It's just

26:08 It is a night and day difference for most people, but uh I think especially for me, like Uh, and pretty high energy and when it runs out, I get crabby. Uh and that's not a good place to be if you're the patient. Yeah, I think I've noticed that as a podcaster, but I've also had a lot of very well known podcasters say the same thing, which is the variance in their ability to speak and articulate themselves and think and sit here for three to four hours having a conversation is night and day when they are in a fasted ketogenic state versus

26:35 or on a ketogenic diet versus When they are In a higher carb diet. And it's so profound to me that I Then I almost wonder why m like more people don't Oh, it's it's insane. Like one of the best things that I've done in twenty five years was

26:49 I went on on a limb and said, I'm going to try and teach two hundred people at once how to do this intense. ketogenic diet for three weeks. Uh it is Hardcore, this is not playtime. You're checking your numbers every day and you're comparing them to your classmates. And what you get to see in this class of two hundred people going with an extreme ketogenic diet.

27:10 Is the testimony you just said. I cannot believe how good I feel. By the end of three weeks, they're naming babies after me. They they think this is. A miracle. And I'm like, exactly. I mean, When you do it in a group like that.

27:24 I don't need to advertise. They tell their friends, they tell their like if you want to be on a ketogenic diet that really wakes up your brain. Yeah, I didn't think I could do this. I thought I was too old for this level of energy. And it's there within three weeks of doing it right. How long does it typically take, on average, for someone to feel those brain benefits from doing the ketogenic diet? Typically.

27:46 How long does it take you? Me? Yeah. I rarely go out of it. Meaning I'll I might have a couple of days where I fly to LA and have a fancy meal and then I need to be back on it. It just doesn't feel good anymore. So but let's go let's go to when I was overweight. Okay. So You say who's insulin resistant. Any person who's had a baby. Okay, you have to be insulin resistant to hold that baby for nine months.

28:07 Okay, so I had three of'em and then the weight never came off on that third one. So here is an insulin resistant person at forty something years old. And I am probably Sixty pounds heavier than I am now. In the first time it it uh

28:22 I tried to get into a state of ketosis. For like nine months. I was about to give up on like why can I not pee a ketone? Why does every I mean I'm a doctor, I'm trying to use this for my brain patients, but I'm afraid to tell them about it.

28:36 'Cause I personally cannot keep Petone. I mean I was trying to follow fifty carbs, then I tried to do thirty carbs, and then I try to do none, but I just couldn't make it long enough into that ketogenic state. And What had happened is at least a decade. of high insulin. Three babies

28:52 Full practice, busy life, you know, on call, those kinds of things that are all dangerous if you're gonna try to have a peak brain. I took my kids on a Um twenty two mile hike around the city. Uh on Memorial Day. In the name of troops as mental health.

29:09 And I said, if I am not peeing a ketone after walking twenty two miles having fasted for a day. Then I'm for sure that this diet is a hui. So that's how much energy it took for me to pe a ketone. Because I was very insulin resistant. I had been making excess insulin for a decade. And I'm a doctor. I I should have known that.

29:28 My sugars were fine. My hemoglobin A one C wasn't bad. But that excess insulin that stored Sugar that store glycogen. It took

29:37 Forever to get that low. And only after I Fasted and then walk twenty two miles to I be a ketone. So I when you ask the question how long does it take? I don't make a I do a much better job now of telling people how to get there.'Cause I n I almost gave up thinking this is junk science. If you if you were to eat a high carb meal now and take a couple of days off, how long would it take you to get back into a ketogenic state where you have those brain benefits now?

30:03 Uh, I could probably flip back in within twelve hours. So that's how long it roughly takes. For someone who's got a bit in better metabolic shape, it will take a couple of days. Um Is there a downside to living in ketosis? The whole time. Because people often say when you talk about the ketogenic diet that it's not sustainable. Yeah. I he I hear that a lot, but I have

30:26 Thousands of patients that have been doing it for years. And what happens is uh As soon as they Exit from the ketogenic diet. And they start to feel the trash build up again, meaning the joints that didn't s hurt forever.

30:39 Now hurt. The vision that was super clear is now foggy again. The brain that wasn't irritable and depressive. is back to doing those things again. I mean it is within a week or two that Yeah. I like to think of when you're in a ketogenic state. You wring out that inflammation and trash in their brain.

30:57 And the brain is like Crisp it is doing a great job. And when you put the sugar back in. The swelling goes back into their brain. Insulin and water flood the body and

31:08 And it's almost like a minor concussion. And their brain? is not working right and they now know it. And is there any Oh the

31:16 benefits to being in a ketogenic state. You mentioned strength briefly. Yeah. So when you're looking at uh do you do weightlifting? Yeah. Okay, so when you weightlift uh uh How

31:27 Grade your soreness on the day after your Like lifting day. Um if I've been using that muscle consistently, there's no real soreness. Good. So uh let's just take a day where you're pushing it harder, you're deadlifting harder and you've got a strain in those muscles. One of the key components for repairing that as quickly as possible. Is

31:48 is to be in a ketogenic state. to take that inflammation way down. And You probably didn't need the help of repairing that muscle when you were, you know, eighteen, twenty two. But as you get into the thirties and especially into the forties, The amount of

32:01 Inflammation. That tries to help you. Repair that? It overshoots. And that's where the chronic pain's from, that's where the delay in repair comes from.

32:11 So when I look at power and muscle training, I I the first place I talk to my patients about it is How many days does it take you to get back to it? to feeling good after you've had an injury. Uh let's Let's be on the side of a ketogenic setting where your inflammation is super low.

32:28 And when you tear something, which you're going to tear things when you're lifting heavy, the repair part is so quick. The power is a little hard to talk about. If you want me to go there, I can. Yeah. Yeah, so is there is there gonna be any impact on my my tr ability to train? Yeah. If I'm in a ketogenic diet, I'm gonna be

32:45 impacted in terms of endurance or strength or power or anything like that. So we looked at this in um and military people, uh is one of the my favorite ones, where they are all insulin resistant. And we put'em on a ketogenic diet, and so they're trying to meet their standards. And at a month of being in a ketogenic state, they've lost weight.

33:05 But their power and time didn't do anything too sexy. Then you look at those same soldiers at a year, or I think it was six months was the next time they did another big check. Uh and by golly, they've lost even more weight. And their power is about twenty percent more.

33:22 than their counterparts. When they get to eighteen months. Of a ketogenic diet. Their power is almost fifty percent more. Then what?

33:30 their counterparts were. So let me explain that. As you're looking at a muscle. It will choose which fuel it wants to use. And when you've been glucose using when you're on a non ketogenic diet, it's going to use glucose first to fuel. But if you can train it to

33:45 To use fat. In that training. It's a longer, better fuel. With less inflammation and Um, especially in a a state where

33:55 It will use both fuels quickly. That takes time. I mean it takes and what I tell patients is you'll love me in eighteen months. You'll think I'm pretty great at six months. But if you're trying to run a marathon and we're only three to four weeks out, you should not start a ketogenic diet. You're gonna think it's the worst thing ever. It's meant to train muscles to use fat.

34:15 And that takes time. And is there a link between some of these cognitive degeneration diseases like Alzheimer's, dementia, et cetera. And The ketogenic diet.'Cause I I know that there's been

34:28 some research that's underway and has been Done to try and establish. Causality of is there a link here? Yeah, you know, it's one of the saddest places where if you look at what patients regret in life. They come into the clinic and they're already starting to say, I was driving the other day and I I got lost.

34:46 And when I hear that we are fifteen years too late. It is fifteen years of building up trash in that brain that we have to clean out that debris. And I had the privilege of an amazing story that taught me I don't have the gift of You know, seeing it in the future.

35:01 Am I gonna reverse these Alzheimer's before they show up? We don't have The research for it. Um, but I have a lot of clinical experience saying, Boy, they are so much better. I don't know if their memory is gonna stay this good. We're only three years into a ketogenic diet, but it's way better than when it started. And then I had

35:21 A down syndrome. Patient. At forty years old. uh in my practice. So

35:28 Her mother came to see me first. She said, I I want to try this ketogenic diet. Um, I've been helping my daughter who's has Down syndrome. We've lost a hundred pounds. Because the doctor said that she might do better. if um if we lost some weight. And this not an uncom uncommon thing to see they have

35:49 Advanced insulin resistance and advanced Alzheimer's. earlier in life. So it's a great A place to study Alzheimer's because They have a a more rapid onset of it.

36:00 So the woman comes, she's lost a hundred pounds, and during that time her mental Cognition got worse. So now she's got a hundred pounds down, but none of those brain things are better. And I said, All right, if we're gonna do this with your daughter, we're gonna make sure we're pricking your finger. It's not gonna be fake. We're gonna do a real ketogenic diet. So the mom starts on a ketogenic diet and

36:21 I think both her and mom are genetically superpowered to make ketones because they have ketones of like three within a couple of days. Which is the the average would be like one. If I if they hit one in a few days, I'm thinking, Good job. And the mom calls me at the end of the week saying, Do you think it could possibly work this fast? She is She's you know doing the little jobs that she used to do around the house. And I said, Well, call me again in a week, let's see see how she's doing. And the mom goes.

36:46 The most profound thing just happened. I've taken care of this girl for forty one years. And I asked her the other day if she was doing something. She wanted to go to the church with me, which means she left the house. And she was at the church and she was giving her instructions to do this, go around here and put it over there in the give her a little job. And she said, Do you understand? And the girl replied.

37:08 I understand. Awesome. What's the big deal? She had never said a three syllable word in her whole life.

37:19 Two syllables is all her brain could ever put together. For the first time in her whole life Three weeks onto a ketogenic diet. And this Alzheimer's

37:28 Diagnosed patient. who had Down syndrome. Now had a brain that was not only working great. It was doing the best mom had ever seen it. And on a ketogenic diet, not only did she lose about fifteen to twenty more pounds.

37:42 But her world opened up again because her brain which had Alzheimer's No longer had that diagnosis. I was looking at some of the supporting studies around this, around the impact I can have one the brain and Studies show that in dementia, especially in Alzheimer's, the brain struggles to use glucose efficiently, ketones provide an alternative cleaner fuel source. Um

38:01 Ketogenic diets can boost mitochondrial function and energy availability in brain cells. Keto lowers systemic inflammation, which is linked to slower cognitive decline. Um Keetons may protect neurons from damage and promote the growth of new neural connections. And Alzheimer's is something called type three diabetes, which I've had a lot. Um and keto improves insulin in sensitivity potentially reducing this risk. And lastly, small studies show temporary improvements in memory and cognition in people with mild cognitive impairment or early Alzheimer's.

38:29 But the evidence is early stage, long term adherents can be hard and the diet isn't s suitable for everyone. uh, for example, underweight people, um and people with certain medical conditions. Right. So how do I measure my blood ketone levels? Uh is that what uh these devices are here at the table. When I look at um uh giving patients the freedom to say, don't don't come to me for the things that I that you can do at home.

38:53 First thing is be willing to check data. Okay. So blood, way better than any other way to measure this. We're gonna be able to see should we have a contest which one's better? Yeah. Okay. So you wanna go first? Okay, so what I'm gonna do here is I have a Finger prick here, which is going to take some blood. It's going to prick my finger. Then I have this little reader, and I also have this little strip here, which I'm going to put my blood onto. And within

39:16 A couple of seconds. It's gonna In my body. Right now. And so we're gonna look at that at the same time as your blood sugar.

39:24 Which is how You can measure insulin. It's the best. proxy for saying how high is his insulin. So put both of them in there before you go'cause then you don't have to prick yourself twice. Okay. So a blue one is gonna measure the ketones and a brown one's gonna measure your glucose. Okay, and this device, how much does it cost if people want to buy it at home and start breaking their own feelings? Yeah, I think there's a kit that comes with about

39:46 fi fifty strips so you can have ketones and glucose at the same time. I'm guessing it's around seventy bucks or maybe it's sixty to seventy dollars. I I They have quite the Yeah, put it all in. There you go. And so there'll still little lights on the other one too, right? Perfect. Okay. So now prick your finger.

40:01 Best to do it on the side of your finger'cause there's less nerves there. There you go. Good job. Okay, so I'm gonna put my blood onto this one, which is the key to reader. And it'll it'll count to uh I think it's um.

40:18 My glucose is eighty six. Takes more blood for the ketone. And my Keto levels are point nine. Okay. So that's a Dr. Bow's ratio of eighty six divided by point nine, which is probably like Ninety five or something. Ninety.

40:35 Fine ish, right? So my glucose levels are eighty six. Is that high or low? That's good. Uh so I would say that's not low, it's just good. Okay, and my ketone levels are point nine. Right. So when you look at them in comparison, like you want to have a blood sugar that's Not triple digit, so that's very good. And the closer the higher you are above point five.

40:56 The better. The result. So that's pretty good number. Ketosis. Mm-hmm. What reading would I have on this key ten meter? But it would be also that you have that reading without a triple digit blood sugar. So when I look at the t combination of them, I do a little math and say, Your doctor Bow's ratio is like ninety five. So you are burning fat right now.

41:17 Okay. Okay. So that's a good sign. When I am trying to help people who are trying to undo Cancer or autoimmune or brain injuries. They have to have a better Doctor Bowles ratio than that. Let's do your readings. Okay. To see where you're at. All right.

41:34 Drum roll. Eighty three. And one point seven. Are you at one point seven? What have you done? So

41:43 I've learned that I would love to be thirty three again. And be able to eat that late at night. You said that I'm like, Oh, it's been a while since I've eaten that late at night. It's probably the hardest thing to teach my patients too, is like you don't appreciate how much insulin you make that late at night.

41:59 Now you're still in the world. Kick your heels and enjoy youth. But at my age. You cannot do that.

42:07 I can eat in the morning. I can have good calories of high fat and good protein in the morning. And I've learned to stop eating somewhere around three o'clock in the afternoon. Um, in fact, if I Yeah, I know. Three o'clock in the afternoon, you stop eating. That's usually the case. You know, what what's really hard though is

42:24 How much of your life is social? Like you said, Oh, there was this dinner party last night and I had pasta. And you're like, Yep. Uh that would be something I have to teach my patients you have to say no to that. You cannot be eating at ten o'clock at night if you want your insulin to not To not do that debris thing.

42:41 And Boy, when their memory isn't going well, when their friends are dying of uh memory problems. You know, it's I don't like using fear tactics. I don't think they last very long. But it is

42:52 Such a reality. Of poor performance. That I can't do that. I cannot eat at ten thirty at night. What is it about being asleep that causes the

43:03 sort of deregulation. Like what is it about it doing it at night? So now it's going to take that metabolic curve. And in order to back to store all of the part that gets stored and then turn the part into fat that needs to be tucked away and get back to baseline, it's gonna be eight hours. At least eight hours. Which is fine. Because I don't eat till

43:22 I'm probably not gonna eat till two PM today. Right. Well, you f we missed one part. The sun will rise. When the sun rises, y even if you're in Solitary confinement. You cannot see the sun. Yeah.

43:32 Your brain knows that the sun just went up and cortisol rises. Okay. Cortisol leaves your brain. goes to the liver and says, You know that stored sugar, that glycogen? Release. You make

43:43 Glucose first thing in the morning. How much glucose? Depends on how insulin resistant you are. So you're gonna you're gonna have an uneaten meal. When you wake up in the morning.

43:53 Glucose. Has been stored for the this purpose. It's gonna wake you up. It's gonna give you the energy when sun rises to to fuel you. If you got a bunch stored. You're gonna have a high blood sugar. Can we do Jack's ketone levels? I'd like to know where where Jack is at. Let's do that.

44:08 What's Jack do for a For his own. No, wait a minute, is Jack the one that did the VO two max with Peter Atia? And you're Well, you know, peak brain performance is my thing, and one of the hardest brains to heal are chronic runners.

44:23 That trauma thing is real. Like it's so hard to explain to them too. If you're a vegan who runs, ooh. You're in trouble. Ninety five percent of vegans that listen to this podcast frequently don't subscribe. Oh yeah, well, glucose is eighty eight, not too bad. Keetons.

44:40 Oh. Absolutely. Yeah. That's an example of He is making trash. There's no trash going out. So his ketone level is what, then his blood sugar is eighty eight. So if you take eighty eight divided by point one, it's like what, a thousand or something, it's really high.

44:55 Eight hundred and eighty eight, probably. Uh that Is a lot of trash being made. When that doctor Boss right ratio is high. You you can't take it out.

45:07 I just think that when Peter Atia did that and said, Oh, I had no idea, I'm like, You could have Just check this first thing in the morning for five days. If you have that kind of a doctor Bowes ratio, you're insulin resistant. You're insulin resistant. You have to be hitting that in a routine regular interval in life. To not have those problems.

45:26 To have osteoporosis at such a young age A a ketogenic state would not allow that, you would be using n resources much better. He actually did a test, it turns out he doesn't have osteoporosis. But Oh good. Yeah. You shouldn't have osteoporosis at your age.

45:42 No, I think that was a misreading because of the scanner, but um Right. But on this on this point in particular, his ketone levels are zero point one. So he's basically running off glucose. All all glucose. And and so why is that happening? Okay, whatever he ate The insulin went up. So let's say he was Your exact same eating pattern. He ate last night, he had the six, eight hours of sleep. The cortisol said, Oh, the sun's rising and it rose his blood sugar a little bit. Okay, when the sugar's high you can't

46:09 You you can't your your insulin's gonna be high too. You're not making ketones. These this keto test with most of the team here. They were all around that region. They w were in the region of zero point one few turns in their blood to zero point three. Welcome to my clinic in ten years. That is trash being made, never being taken out.

46:27 And so you'd say to them you need to Do some fasting, you need to Yeah, cut carbs. Yeah. I mean if you're looking for sh quick Okay, if they're in their twenties. I mean, I have three kids, right? And they have heard this chirp for ten years. Uh I mean how I got into this was my mother was very sick and she was sick because of a high insulin problem.

46:47 That caused cancer. So we put her in a ketogenic state and everybody in the family got on board. So here's three little boys who no longer have candy around. Now they're in their young twenties, and for the first time they're actually listening to say, Gosh, Mom, one of them's at Georgetown. He has to read for long periods of time for Georgetown law school. And he's like, If I'm not in a ketogenic state I can't

47:07 Keep the focus. And I said I said, Well how are you doing that? First he tried some of the supplements, okay. But what really happened was he cut the carbs down and said, I can say no to that because of the sustained brain power. I mean it's really easy in your ear twenties to do this. Cut the carbs even to fifty.

47:24 Був то є. That you made ketones. And that Return on your dividends is you won't be seeing me in twenty five years. So you have this idea of this keto continuum. Mm-hmm.

47:36 What is the ketone continuum? I read about it, I mean it's uh It's a book here. I have which you published in twenty twenty. called the Keto and Continuum consistently Keto for Life. Right. So the the Keto Continuum is this twelve step Process. Right.

47:51 The first part is the beginner. Okay, so the first part, the beginner section, has four stages to it. Right. What are what are those four stages? I like to tell patients that you never fall all the way off of the continuum. So the first part the first step is really Not keto, but it is that they're eating every two to three hours. And if they fall off the wagon, that's usually where they land. So that's what most people start at. They're eating every two to three hours. They are not keeping their carbs less than twenty. Step two.

48:21 Is cut your carbs to twenty. That's the only thing I need you to measure and you're gonna ketone strip, you know, measure ketones in your urine. Uh and that will ride you'll you'll ride a wave.

48:34 When that ketone production is happening, The fat based hormones in your body. Are starting to resurrect, they're starting to do the things that they need to do. And there will be this magical moment. In the not too near future.

48:48 Or you skip a meal. And this that beginning stage. How long? Does that last? I'll put this on the screen so everybody can see the continuum. Um, how long does that initial beginner stage last for people?

49:00 If they've been severely insulin resistant, this is the ones where I've said they Took their carbs to twenty. for th for two weeks before they peda ketone. So I use some other steps if that's how severe that is. But let's just take the average person. That's like not the not hundred pounds overweight. They're hitting menopause and they've put on twenty five pounds. When they drop their carbs to twenty They're peanut ketone by the end of the week.

49:24 And they are missing their first meal by day ten. Okay, so day ten. And then It says when we get to stage five in the Keto continuum, it says sixteen eighteen sixteen eight, is that Yeah. So then we start to use time restricted eating. Uh, where I want we're gonna ha your body will adapt. People say you can't stay on the keto diet because they go to step four and then they think that that's all they needed to do.

49:47 There are several steps to reversing this problem, and you'll know you have the right step if the ketones are still present in your gl in your blood. Your body will adapt, though. So we start to say alright, we're gonna learn some new behaviours. We're gonna learn what the nothing burger looks like. At least for sixteen hours out of the day.

50:05 What does that mean? You do not Eat a thing in those sixteen hours. Now I I I give'em a little hedge because most people come in like you. They don't start eating until two o'clock in the afternoon and then they eat until ten o'clock.

50:17 And I want them fat forward. I want lots of fat going in because insulin resistance. That high insulin state. means they've locked or they've insulated their fat on their body. And then we get to stage seven where It says twenty three one. Is that

50:33 Fasting for twenty three hours a day. Yeah. And eating for one hour a day. And the there's a little bitty line between sixteen eight And twenty three and one. But there's a whole bunch of life there. Meaning we don't actually p to have patients go from sixteen hours of fasting uh to twenty three, we have'em slide it down by an hour, slide it down by an hour. And then we do that harder thing, which is Move it towards sunrise. Quit eating until late at night.

50:56 And then the last stage here. So step Nine, ten, eleven and twelve is Prolonged fasting, between thirty six and seventy two hour fasting. Right. So those folks that have high insulin for twenty You know, fifteen, twenty years.

51:12 They're gonna have to do a nothing burger for 36 hours in most of them to really give a good reset of their metabolism. And although you you look at other folks saying, Oh, you should never do that if you're a woman, you should never do that over the age of 50. I'm saying you have too much insulin in your body. You have to do that to get the pancreas to make less insulin over time. On that point, between men and women, aren't there metabolic differences that need to be mentioned here? Because you know, when I Sometimes when I do ketogenic fasting, my girlfriend she takes much longer than me to get into a ketogenic state and I'm wondering if her body is in some way trying to defend Hm i the switch. Have you ever seen the the reality show Alone?

51:50 Oh no, I'm not sure. No, I'm not either, but they drop these people off in the middle of nowhere and they starve'em to death. And you watch the fat come off of them, and the men, the fat just w melts off of'em. And the women They do what your girlfriend does. It just holds on to them. That we are designed to have that fat on them. So Asking them to do a ketogenic state, you'll hear people say, Oh, it's gonna ruin your hormones. Oh, it's going to You can't do that. And um I would say you

52:18 Can have all those conversations once their insulin is normal. But I have lots of women in childbearing years that are excessive producers of insulin. And their vitamin D is low, their estrogen is low, they have hair loss on the top of their head, they have skin tags throughout their body, or maybe the first sign was they had PCOS. Okay, all of these are a sign that insulin came in and it's too high in their body. So lowering it has rules. And if you want to have a baby, carry a baby, uh, have uh the weight come off after you've

52:50 We just dated a baby. Um, have weight not be your enemy during menopause. You have to be making ketones at a routine and regular interval. And Yeah. Start with the food. Start with the menus in the kitchen.

53:03 Don't run to the gym first. I've noticed uh in in women in my life that th they've told me that their menstrual cycles become more synced up when they are in a lower carbohydrate diet. Right.

53:14 Their hormones can hear each other. I mean when insulin is high. Insulin dictates what that sugar does. But it also is the dictator for every Morsel of fat. And

53:25 Estrogen, testosterone, vitamin D. They're all a derivative of fat of cholesterol. And they are They're put into the fat cells. If you biopsy an obese woman and say, Can I see, is there any vitamin D hidden in there? Is there any estrogen?

53:40 Yes, they're all in those fat cells. You start to lower their insulin and And the fat mobilizes. So the hormones that are naturally communicated between women They can actually hear them again. I mean that

53:52 That tribal thing. If a woman were to stay in a ketogenic state permanently Would there be any disruption to her metabolic health? You mean like me? Yeah.

54:02 Like w uh you know, a menstrual cycles her Uh Yeah, anything. Yeah. You're gonna find people that it shouldn't be extreme, meaning

54:13 I've been on this for fifteen years. The ketogenic phase is at least Uh in a

54:21 month the first few years I was on it. Now at fifty five, um menopause in the last year, um, I'm like without a ketone, my brain doesn't work right now without a ketone. Uh my energy goes to pot. And I've been walking women through menopause for twenty five years. It is not a fun story when they're insulin resistant. So Prepare. Uh have

54:42 The flexibility Of that mitochondria to use both ketones and glucose. And that's what a ketogenic state is. Well we have twelve cans of sardines here, and uh Uh I I wondered why you

54:54 You brought Sardines. Well yes. That's a hell of a tool. Why? So um when you're trying to help patients

55:04 Change behavior. Sorry, the sardine juice has gone on my iPad. Oh good luck getting that off. Uh the worst smelling, but they're not the worst tasting.

55:19 Now when it comes to bitter in fish, they don't have the bitterness that tuna does, so Tell me about sardines. Why why should I be eating sardines? When you're trying to teach patients those stats that you read off a minute ago, they don't care. They need a very clear step on how do I begin. Mm.

55:34 And when you're working with somebody who cannot seem to get their ketones to rise. And I give them a whole list of menus. That's too noisy. Let's take it down to one food. That is high in fat.

55:44 High in some of the best fats, high in protein, it's whole foods. And it's affordable for everybody. Under the sun. Okay, so you do you Do you like a sardine fast?

55:54 Yeah. So in fact that that twenty one day I mean. 21 Day is that three-week course where I say, I will teach you how to do an advanced ketogenic diet where everybody will be peeing ketones or making abundant ketones. On day six? Uh, I say all right, the only thing on the menu for the next three days.

56:12 Isardians. There's no eating window. You can eat as much as you want. There's no limit to the amount. And what I'm pushing them to do is not only eat a nutrient dense food But I want them to feel satiety. I want them to feel full. Do I need to be consuming a lot of fat as well?

56:28 There's plenty of fat in there. But I mean generally'cause this is one of the f the fact Yeah. Puzzles me is I'll I'll go Say I went a week without eating

56:36 Carbohydrates. Sometimes I'm still not in ketosis. And I think I heard somewhere that it's because my fat Right. Yeah, so again, you at the time you went you went seven days without eating it hardly any carbs, right? And you still didn't make a lot of ketones. Okay, so you had fat on your body?

56:54 Yeah. Okay. So why didn't the fat get to your mitochondria? Excess insulin. Okay, you had been in a high insulin state. So if you swallow the fat, then you can turn it into ketones. Right now, all your fat's locked under this insulin bed. If you kept going, it would eventually hit. But that's painful. I mean, I have patients who do it for two weeks.

57:13 So what you're saying, you're saying that I need to eat the fat. Yeah. So if you put the sardines in oil Uh that's a great high fat, high protein. Uh it's also a little easier to m masticate the the meat. And you'll have high fat, high protein, and you'll have beautiful ketones by th by Forty eight hours, maybe seventy two. And what what is the the composition of my diet in terms of protein.

57:35 Fats and carbohydrates when I'm trying to get into each day. Yeah. I don't let people get distracted by this, right? I say, look at your finger. If it's got a high ketone, you have got enough fat and enough. protein uh And low enough carbs. What most people have is the story you told.

57:52 I've been doing this for five days. Why don't I make any ketones? And the answer is, what is hidden behind the chemistry is too much insulin. You've got To have and so that's a great place to say put the fat up. Keep the carbs low.

58:06 And the ketones will come. When you say put the fat up, you mean E more. Fatty foods. Give me an example of the type of shopping list that if I was trying to get in a ketosogenic state and stay there. I would have.

58:17 Yeah, m my one of my favorite things is uh Uh pork belly? More eggs. Beef brisket, uh ribs. Avocado are have a beautiful marketing team, but they do have carbs in them. And I've had people

58:31 overeat them. Like I have four avocados today. I'm like That's y you you're on the wrong bandwagon there. Avocado makes the list, don't get me wrong, but It's not a diet of mostly avocado with a sprinkle of chicken breast. That's not gonna get you into ketosis. The fat has to be higher than that. Most of the time when I'm really struggling with a patient who just can't seem to make ketones, can't seem to make ketones.

58:52 And they won't do the sardines. I've said Eat butter for a day. That's a hundred percent fat. Okay, so you can just have increase the butter and Yeah, you could have that. Okay, so that Are there clubs in here?

59:03 Yeah. No. No, it's just fat. Mm. Mm-hmm.

59:07 And it's not awful, but it is a great social experiment where They haven't felt what satiety feels like in a while. People talk about net carbs. They say you know. I have a claw who has

59:20 twelve. grams of carbs in, but it has ten grams of fibre, so the net carbs is Two. If you've never had insulin resistant, you can do it that way. My patients have had high insulin, and I don't play that game. It's gotta be total carbs. Fiber is for farting.

59:36 Do you recognize this photo? This lady. Oh yes. Jane had uh Oh she had pathology with how she thought about food, like many patients.

59:51 She she had food as the way she coped with a lot of things. And as long as she was clearing her plate and using that food, it comfort a lot of wounds. When you start to address some of these things, I mean the ketogenic diet doesn't fail if you just follow the chemistry. The ketogenic Diet fails when you have humans. who've had wounds, who've had a history, who have stress, who don't sleep.

1:00:16 And Jane was a great story where All the goodness in the world that couldn't undo some of that. relationship she had with food. Uh, so the first time she she's one of the coaches that I use for that twenty one day and she just has the best outcomes because she was doing a a strong ketogenic diet, you know, for those three weeks, twice a year. And she decided that after I think the third class she was gonna do sardines only for thirty days. And she writes me at the end of the thirty days, can't believe how great she feels.

1:00:44 And Really kind of address some of those Demons associated with why she would eat what she would eat. And then knife hit again and she put on some of the weight again. Um, she'd use s sardines intermittently, and she called me and said, All right, I think I'm gonna do this again. I'm gonna just go on sardines and really

1:01:01 Have a some come to Jesus moments on why it why it is that I do some of the things I do. I mean it's a really vulnerable moment where You can hide those moments. You can never tell a soul what's really going on through your mind. And she was going to address them. And I said, Well I have a bone to pick with Joe Rogan.

1:01:19 He has said some Inappropriate things about sardines. Like they're Arsenic poisoning. So I'd like to check a few blood levels in you before you ch start. So we check her vitamin D, we check her arsenic, selenium, and a few other things. And she starts on her sardine challenge her sardine journey. And she goes a hundred days. A hundred days of only sardines.

1:01:40 And not only does she First of all, her vitamin D, she did not take any vitamin D, she stopped her vitamin D. It went from like The thirties and forties up to Just maybe over a hundred, a hundred and eight or something. Uh her selenium didn't do anything naughty her arsenate did not do anything naughty like Joe Rogan said it would.

1:01:58 And she was able to um Not only Shed the pounds, but really Say some truths about why she was eating so much. And she confronted

1:02:11 The pathology about why Why is she using food for those other things? You know, I do this thing in the twenty one day where I ask them to find their best day in their life. And I'm trying to just get'em to think about what does that feel like? What what did that look like?

1:02:26 And then we go to the worst day in their life. And Jane wrote something that really touched me. She said I don't think I've ever had the best day of my life. This was probably the third or fourth time we'd done that exercise. So she'd done it in a way where

1:02:39 It didn't bring any extra attention, but she was she spoke a truth that just said I've had this fear for so long. That for the first time I'm gonna say out loud that I'm looking for the best day of my life.

1:02:52 And I feel like I have the freedom to do it. That's what happened after a hundred days of sardines. So if she eats uh sardines for a hundred days. She's probably not gonna get like The gut microbiome. She has the best gut microbiome.

1:03:08 D doesn't she need to be eating plants to? I don't know. Fibers for farting. So You're looking at a gut biome, right? And so tell me what you think that is.

1:03:19 Uh lots of bugs that have been Feeding on plants. Okay, yes. Pewterate has uh has part of that equation. So Gut biome is the slime layer inside your gut. It's where the critters live. It's where they set up homes and they if you have a really good slime layer, it's squishy. It's dense.

1:03:39 Moth eaten. It's not aqueous or water like it's squishy. And when you put plants in there, well you put fiber in there, it tears that down. And you say, Well, fiber's needed for this because

1:03:54 Eat up on the fiber and they put out some butyrate and that helps these other bacteria to To grow. Like, yeah, that's one way to get a good microbiome, but We haven't been fiber eaters forever. And when you look at many of my carnivore patients, especially when they've got

1:04:10 You know, some of those little fish. Scattered into that. carnivore diet. Um There's symptoms of irritable bowl, of chronic diarrhea, of you know bloody ulcers.

1:04:22 Reverse. Why?'Cause that gut biome. Got a lot stronger and a lot healthier. So the things that I from doing this podcast for a long time, the things that I I'd be concerned about if I just ate sardines for a prolonged period of time. Or really any diet, I guess, for a prolonged period of time, a a narrow diet would be

1:04:38 The fiber issue we talked about. And then all the other things that are just not in sardines, I mean vitamin C. Yeah, but you still get a good vitamin C. So vitamin C has different rules when you go carnivore. What about magnesium? Yeah, lots of that. Uh magnesium I still think is one of the supplement we all need. Sodium overload. 'Cause these are very salty, right? Your sodium

1:04:58 churn how well you use sodium is dependent on how well you've eaten in the last week. So when you increase the sodium, those receptors get better. When you decrease the sodium, those receptors shut down. That's a that is an adjustment that everybody will make. What about things like mercury and the other sort of metals toxic little fish little problems. You got the right one for mercury. Again, we tested that for her too. Hundred days, no problem. Oh, the especially in the can as well. I uh I think I've got a bit of an issue with canned food these days because I've had so many Microplastics. Microplastic tox toxins, et cetera. I think you're majoring in the minor leagues there. that the the amount of benefit that people get from

1:05:35 Sardines versus Whatever might be in those Yeah. I tell patients not to worry about it. And then

1:05:42 And the last point I said was about digestive and mood issues because the That microbiome is so linked to brain, absolutely. Serotonin, isn't it? I mean serotonin's in the gut, but it's it's a huge part of uh like a GLP one, the GIP. They're all produced hormones in the gut that are hugely impacting your brain. And when you want GLP one to be made, have a strong, thick microbiome. You do not need fiber to do that. You need butyrate. Butyrate is that two carbon

1:06:09 Uh fat that comes from Acromancia. You You know, chewing up the fiber, right? Or

1:06:18 Beta hydroxybutyrate. In your blood. That's that ketone thing you've got over there. Oh. These things. Yeah.

1:06:27 There you go. Yes. It's a beta hydroxy butyrate is what that is going to turn into your circulation. Butyrate is uh a fat chain that's two carbons long. That's what the you're asking that microbiome to say here this long string of fibers coming along And that

1:06:43 That little bug is gonna eat a piece of it. and make butyrate. Two carbons of that. That's one of these things that you're talking about. You need to have butyrate. You need to have butyrate. That's what every every why are you even vitare? You gotta have butyrate. All these you know experts come on my show and they talk about the importance of having a diverse I know, I s I've I've watched a bunch of them. Diverse microbiome, yes.

1:07:03 And What I think So it's not gonna be diverse if I'm just eating one thing. Oh yes it will. Measure. W so that's the whole point of a microbiome is w w you know. Diverse enough to be supportive. I mean diverse enough to have the

1:07:17 The two chain fat that you want to have in there. Go back, uh And and look at When our bodies were just eating.

1:07:26 Um Yeah, fish or carnivore. The beauty of a microbiome is how much і до. In Every patient.

1:07:37 What about supplementation? A what are the key supplements that Yeah. Don't live without. On a daily basis. Vitamin D turns out to be a really important one. I if I'm eating sardines uh

1:07:48 four or five cans a week, I probably don't need vitamin D, but Why is it so important, vitamin D? Yeah, it's a hormone. Right? A hormone that goes and talks to every one of the cells in your body. And it

1:08:00 Tells that cell. To be its best. version of itself. That hormone Uh, goes to the nucleus and it makes that skin cell do something different. It makes your brain cell do something different, it makes your heart cell do something different. You read all the benefits about vitamin D and you think

1:08:15 It's like It's like uh it does everything. Like how can it do all of these things? And the reason why is it is not just a vitamin, it's a hormone that changes how the cell functions. Unfortunately. It's made of fat. So if you have high insulin, it gets stuck parked in your fat cells and it didn't get to the cell.

1:08:33 Is there a link between vitamin D and ketosis and weight loss and insulin? Yeah. It's actually why I pointed out that when Jane did that hundred day Uh, she's been struggling with her vitamin D it in the thirties or forties. Right. But for the best brain, we want it to be of fifty. So she starts on the sardine challenge, it's in the thirties or forties, and she's supplementing. She's taking as much as she can. But what's happening

1:08:56 Her insulin was putting it in her fat. She goes on sardines, which have vitamin D in'em. By the end. Her vitamin D was a hundred and five, hundred and eight, something like that.

1:09:07 So You can see the experts say don't go above a hundred, but Definitely. I don't I don't have any worry about hers being a hundred and eight. What happened was she lowered her insulin.

1:09:17 And now fat can move around in her body like it's supposed to. And part of that fat isn't just her estrogen. It was for vitamin D. She's not. Twenty years younger. You should see how joyful she is. That's the part that you're like

1:09:30 What unlocked during those a hundred days of You can say food restriction, but vitamin D went up, uh insulin went down. And she really said How many things am I gonna comfort in my life from food? And let's let's

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1:10:53 So magnesium is required for every little It's like the spark plug in our bodies. It's a little metal. And it's how ATP gets recycled and you need it for almost every enzyme. But Our food is low on it, our food's our soil is low on it.

1:11:07 You just gotta replace it. I I use magnesium supplements, but I also have my patients go for A magnesium float. What's that? Uh, ever seen pictures of people in the Dead Sea? No.

1:11:18 They're floating right. This the salinity or the salt level is so high and it stinks, right? It's a stinky place. It's magnesium. So they go in there They soak in the magnesium and you're like, Oh my gosh, I feel so much better. Like, that's gotta be junk science, right? Well it turns out it's not. So you can get magnesium absorbed through your skin.

1:11:37 Just like I don't know, in the nineteen nineties you'd go rent time in a tanning bed. You can rent time in a magnesium float. Any of this? So Omega Three, if you're not doing fish, uh you can't go wrong with omega three. And

1:11:49 You know Uh I Stephen, I really Push my patients to have ketones around. Wh when you say ketones, you mean external exogenous ketones, yeah. So the word exogenous means external, externally consumed. And there's some on the table here. I'm an investor in this company, actually, so That's probably worth saying key to not Q then you got some other ones here which are

1:12:09 What's this? It's like a that's ketone salts. So this one is just beta hydroxybutyric acid. My husband is deathly allergic to stevia, so I said I'll make this one for you, honey. It's just liquid ketones. Okay. No s no sweeteners, no fillers, nothing. And is there a difference between taking External keetones. through a drink or through the salts or whatever else versus actually being in

1:12:32 The ketogenic state because of your diet. When you make it, it is much more abundant. But when you Do what people do. They fall off the wagon or they're very insulin resistant, so their body is trying to catch up to To equilibrate. You want ketones put back in circulation.

1:12:49 Because it will spark their liver to make ketones. So it really is a jump start for patients with chronic insulin resistance, chronic problems. We got about you know six years of getting them to the healthiest version of themselves as long as they don't fall off the wagon. So when they are Doing okay, and now they need to get back on track.

1:13:08 And by putting ketones in their circulation like that, by checking their blood? The liver will make ketones, so it's not just a fuel. They will feel better. It's a signal. For the liver.

1:13:20 To make more ketones. But I'm not gonna be burning fat then, am I? You will. I mean again, ketones beget ketones. When you are making ketones, your body makes more ketones. So if you jump start it by swallowing some You get better tomorrow, get er better tomorrow. And usually if somebody's fallen off the wagon, I'll have them do ketones for like Three days. And the fourth day they are on their own again and they'll

1:13:40 Stay steady for Couple of weeks and then Don't have Pasta. I I that's why I invested in this company because I'm actually a co owner of the business now, and because I saw the

1:13:52 Benefits of having exogenous keytones on a regular basis. Right. So if anyone wants to try them, go to Keetone.com and your brain will use it like that. It's super fast. Beautiful. Right. When I use my key ten reader, it appears in about fifteen minutes or twenty minutes or so so and their liver then makes more ketones for the next twelve hours. That's the part that

1:14:11 I I especially for my cancer patients or people who are really I mean, we need ketones high for their they got chemo tomorrow. They can't afford to say, Go fast for forty eight hours, they don't have the time. So let me help you. And there's nothing better than going into that chemotherapy, going into that radiation. Uh with a bunch of antioxidants in circulation coming right out of your liver. Explain why that matters. I mean I've got a photo here of uh

1:14:36 Grammar rose. Grandma Rose. Yeah. That's my mother. Yes.

1:14:42 She is the reason I'm here. In five years. Yeah, twenty fifteen. The heart the most stubborn patient. Walks through the door after ten years of the best health care I know how to give.

1:14:59 And she's grey. She looks like a zombie. She's got big lymph nodes in her neck. You don't need to be a doctor to know that She's dying.

1:15:11 Cancer was back again. And we go to see the oncologist, uh and He says, You need chemotherapy and she says Like how The last two times you did that to me, I didn't know what a sewing machine was.

1:15:26 And she made all of my clothes until I was the age of ten. And she's nervous because she has six months to live if we don't do something. And she asks me a question that Lots of patients have asked me this question and I just sometimes lie. She said if it was you.

1:15:49 What would you do? That's a really emotional question because there's guidelines, there's rules, uh here's what you're supposed to do as the doctor. Oh, and it's your mom. And I have I saw what chemotherapy did to it was terrible. She didn't know.

1:16:09 The grandkids. She did it was terrible. We just got her back to Functional again. And so I said I had been reading about the ketogenic diet on brain injuries, and I'd come across a couple of studies on what it can do to a cancer patient, especially an insulin driven cancer patient like she was.

1:16:29 I said, Mom, do you trust me? Like a fool. She said it my whole life. We were standing there in the In the waiting room of the hospital, one way was to schedule the chemotherapy and the other way was the front door.

1:16:49 Said Mom, let's get in the car together. I left my car there, I drove to my family farm, which is a hundred miles away. And explain to my mother what a ketone was. And her brain wasn't working right, so she didn't quite remember. And we went to the house, we threw out every carbohydrate, and man, at six weeks.

1:17:08 With chemotherapy. Her numbers were supposed to drop by thirty percent of her cancer. We didn't tell the doctor, we just put her on a ketogenic diet and said We'll come back in six weeks. So she's walking through the door of the hospital. It's six weeks from there and it is like

1:17:23 God Has Uh Just The holy spirit is rising out of her. She looks amazing.

1:17:34 So we go to get our blood drawn. Or sitting in the waiting room for the k for the cancer doctor. He's my friend. He knows he's known me for ten years, so I'm scared to tell'em what we're about to do. So we're sitting in there waiting and they come and draw our blood again.

1:17:49 Which either means it's really good or it's really bad. And so I get really nervous at the end. We've been in that room for about an hour, and I said, Mom, if he asks you what you're doing. Just shut up'cause I don't know what to tell him. And he walks in. And he slides the piece of paper over to me and says

1:18:08 How did you get her numbers to drop by seventy percent? There's no drug on the market that would do that. When you say numbers. Her cancer numbers. So the chemo would have dropped it by thirty percent. And the ketogenic diet dropped it by seventy percent in six weeks.

1:18:25 And she went from a seventy year old that looked a hundred. to a seventy five year old who looked forty. How did your mo your mother get on from that point onwards? Yeah, she uh she lived her best life. I mean, I talk about her being From this little town of eight hundred people, she was

1:18:43 Mary Poppins. I mean like You don't have Lady's aide unless you're part of the Lady's Aide in the in the little small town. You don't have a Sunday school. Teacher. Unless you're doing the Sunny School. She was

1:18:56 In every aspect of this whole town. And she went back to doing all of it. And The pandemic hit? And

1:19:06 There's a thrift store. That she would volunteer at because Well, it's just a good place to put your time. And the community needs it. And while she was at the thrift store.

1:19:18 She got COVID. And her cancer was of the T cells, which means it's gonna Be the first line of defense against COVID. And her Her T cells failed.

1:19:30 Some of some of the science behind this talks about how cancer cells often rely heavily on glucose for energy, uh a phenomenon known as the Wahlberg effect. The keto diet drastically reduces carbohydrate intake, forcing the body to produce ketones for fuel instead of glucose. Healthy cells can use ketones efficiently, many cancer cells cannot. So in theory, keto could starve tumours while supporting normal tissue. And they've done some animal studies that show it can slow tumor growth in some cancers, especially brain cancers like Glimoblaster enhance response to radiation or chemotherapy in certain models and reduce inflammation and oxidative stress, creating a less a less cancer friendly environment. However w results are mixed. Uh may also benefit muscle mass and weight stability in patients losing muscle from treatment may improve.

1:20:16 energy levels and mental clarity for some people and could reduce insulin and IGF one levels hormones linked to cancer growth, may improve quality of life when used alongside standard treatments like chemotherapy. Um there's also a list of potential risks, which I'll throw up on the screen. And I guess the summary here is ketone may help by lowering glucose and insulin, reducing inflammation and supporting my metabolism. But it can be risky if it leads to malnutrition fatigue or worsened treatment tolerance. When patient I got a lot of people calling and saying, Is it gonna help my cancer? Is it gonna help my cancer? Stephen, I go back to the same thing. The amount of trash that you've not been taking out, we have to start

1:20:51 And when you put them in a ketogenic state I mean it really helped her cancer. It really did that Warburg effect. She was a h a new human within three weeks. But she had a lot of trash to take out. This was a year and a half before she got to be the best version of herself. And it really did return and restore her to When I look at patients now who say, you know, can is I am I gonna reverse my cancer with a ketogenic diet, I'm like, No, but you are gonna deal with it a lot better. I guess that's really what it comes down to. It's like creating a better environment so that if disease does arrive, obviously there is a

1:21:23 Yeah. with a lot of diseases there is a causal element where the way we and our lifestyle does create the disease. Right. Um, but also when that disease arrives, what like environment is your body and to deal with it.

1:21:37 I think a lot about this, I think in part because of the pandemic where For the first time in my fairly young life, I saw that your current physiological environment. So your current the current state of your body was the single biggest predictor of your outcomes. Amen. Oh it was terrible. So I hit thirty years old and it was like well if you're currently overweight, your ch Chance of Dying from Covid is really, really high.

1:21:58 And so I think that was one of the big sort of protagonists in me getting into shape was realizing that, you know, disease is probably gonna happen to me. But how my body responds to it is To be determined. And I look at how much when you're asking an elder person to lose weight. And you just read something really important there, which is when those ketones are in circulation, it is a signaling agent to make more ketones, but it also signals the body to say, Don't use muscle mass as a resource. Go for the fat.

1:22:25 So you can see this protective m I mean, you take people through chemotherapy and they have You know. They should Way too many pounds, right? You put them in a ketogenic state and their muscle mass gets higher preserved, their brain function, their ability to handle this, you know, one of life's most

1:22:42 Enormous fears is death. And that mood stability and muscle mass protection Because they've got ketones in circulation. Well, that's the gift that

1:22:52 They need right now. In High numbers. What is um I've heard you talk about methylene blue. Oh brain health. Ever done that? No. Oh my goodness. What is it?

1:23:03 Well It's old as dirt. So nobody's making money on it. But it is a die. And so if you swallow it, you'll pee blue. But it's also a bridge for how to

1:23:14 Help. Mitochondria. move fuel along. So One of the worst parts, you asked me this question about supplements, and I really have a tough time saying which supplements actually get

1:23:27 to the cells that the patients are looking for. There is a really great fact about methylene blue that when you swallow it, it it actually was used for malaria treatment or anti malaria for soldiers, and they would check compliance by making sure that Their P was blue. But when they died. At autopsy they had blue brains and blu hearts.

1:23:48 It wouldn't. Dye these organes blue. You say my gosh, that's so strange. But you know that tells me. It got to the cell that it was advertising it was gonna get to. So you look at methylene blue, it's supposed to superchar your brain.

1:24:02 And I'm like, Yeah, yeah, yeah, I've heard this before. So I I read about it and I'm like, wow, there's a lot of literature on this. And then I did What I normally do, which is well, let me take it for a couple of weeks. This is amazing.

1:24:14 It was amazing. Like I I was floored at how well that little turkey works, so there's no money to be made on it. It's a it's been around as long as dirt, but It's a powerful brain. Energizer. Like it helps the mitochond the electrical stimulus of the mitochondria in your brain

1:24:33 Keep energy high. Especially for like high energy brains. I I love it. I I'm like I put that in my mor morning coffee.

1:24:42 Which is where the April Fool's joke because nobody can see in their coffee. But they definitely pee blue. And do you take creatine as well? I do take creatine, yeah. Yeah, it's great. That brain supplement is awesome. You do? I do, but I my doctor the other day, I think he was suggesting that I might have taken too much. Why?

1:24:57 Some liver scan I had and he was saying that. Liver scan or kidney scan? Kidney scan, no. Kidney scan. So that's the trick. Don't don't fall for that. I mean I've done a couple of big shows on this where creatine is what you're gonna measure kidney function f with. When your doctor checked your kidneys, he probably had you pee in a cup. And check your blood. Yeah. Yeah. So he's looking at what did you pee out and what how clean is your blood?

1:25:17 Okay. Well even the blood test, it the trash was Looking like it was a little higher. Because the trash we're measuring. Is creatine. Uh creatinin uh and which is

1:25:29 Made from Your supplement. So you put the supplement in and it looks like there's more trash around. But That's just a supplement. It's falsely elevated. It's not true. You d your kidneys did not get hurt by that.

1:25:40 This I answer this question probably thirty times a week. I have a standard email saying, Here's what happened. Don't measure that. There's other ways he could have measured your kidney that would not have been manipulated by that supplement. Uh, what it does for brain function. Especially if there's any ADHD, man, they love it. They they just focus for a long period of time. I mean it's got other great findings like

1:26:01 If you how f how often do you fly over to London? Yeah, I fly a lot. Yeah, that's the best part about it is that the the The jet leg part of it? There's really good studies on this. Like your reset of sleep.

1:26:13 is going to be augmented if you take Like twenty grams of it. After the flight. Ten in the morning, ten at night. Uh and those are great studies, like

1:26:22 Nevi SEALs sleep deprived. Watch what happens when you add creatine. A lot of women don't take creatine'cause they've historically thought of it as like a bodybuilder thing. Right. It's a brain thing. And you take creatine every day. Mm-hmm. How much do you take?

1:26:36 So two scoops. Yeah. Every single day. Every single day. Seven days a week. I put my methylene blue in it too. Down it first thing in the morning. I got blue dyed creatine. I mean those two supplements are just they they blew my mind with the amount of research out there and then I did them. Uh I mean I'm not a big bodybuilder, I do some cross fit y kind of stuff three times a week.

1:26:56 Um so There's that, but I do it for the brain stuff. The brain stuff is really impressive. At the moment in society people are talking a lot about GLP ones and his empek and all this kind of stuff. And um I was wondering if there's any

1:27:10 harms or downsides in your view of using these Zempek, Wagovy, GLP one. Protagonists. And if there's a natural version. For those of us that are looking to Have less cravings.

1:27:27 Um but but we don't want to take GLP ones. We don't want to be injecting ourselves. Yeah, so those hormones are powerful. I mean you if you think that weight loss isn't a hormonal problem, uh show up at a medical clinic. That That they are powerful.

1:27:41 Hormones. that hijack people into a healthier uh or at least a weight loss stage. But when you're looking at Using this powerful hormones Okay, and sh use it for a short time, use it for a long time. What are the rules? These are brand new.

1:27:55 One of the analogies I use for patients is Стівен, іффанато вс<unk>. How would you accomplish that? Right, because that would be short term, easy and reversible. You would not take Chemotherapy the most powerful amazing there'll be every hair on your body will be off in the next two weeks.

1:28:15 And it's short term, they'll come back. There's a price to pay when you're using a really powerful unit to do something for a vanity reason. So it's where I like to begin when I talk about GLP ones. It's a it's amazing. You will lose fat.

1:28:32 So There's great ways to lower. GLP ones or great ways to raise GLP ones, right? Uh for starters. Um When you're overweight.

1:28:42 It suppresses it a lot. So getting the weight off is a huge part of it. That's why this ketogenic diet is so powerful. We'll get the weight off. And that will lift naturally the GLP ones. Is there other ways to suppress um well I was gonna say suppress my appetite, but more to just get rid of the cravings. Well, you'll suppress the appetite by raising those hormones. So you put in allulose. That's a great little boost to that. You put in Beauty. Whether or not that's the bug that you were talking about, or Uh the supplements.

1:29:11 Butyrate increases and stimulates GLP one. I'm Peter. Just for for those that might not know that word again. Right. That's a that is what a ketone looks like floating around your blood. Okay.

1:29:22 Yeah. Uh, so a ketogenic state will raise those hormones and suppress appetite. I've seen a bunch of studies on that that show that When people are high in T tones, they have a

1:29:31 A suppressed episode. Right. And that is linked to the production of some of these hormones, these really great hormones. But you make them naturally, and so it's not the addiction part, it's the Natural way to make it. I guess it could be something to do with my dopamine receptors as well in my brain, but I find that when I'm in a ketogenic diet, my cravings for the things That I once craved like I don't know, like carrot cake or cinnamon rolls.

1:29:53 They just completely seem to vanish. Oh really? When you give them GLP one? Yes. Okay. And I mean the beautiful part is You're young. You'll make a lot of GLP you've already made healthy GLP one. You'll hijack and suppress it. By being overweight and high insulin.

1:30:10 So constantly delivering ketones to your blood? That's how you keep an eye. And you don't end up on the shot. Which is expensive. And very powerful. I always think you know, when we give people advice on things like weight loss

1:30:23 There's always a part missing, which is this part about like discipline and motivation or whatever one might call it, which is the is gives somebody the sort of activation energy to even stick to it. Do you think about this much in your patients? Do you think about motivation? It's huge. I mean, again, most people show up because there's been a recent crisis. Somebody died, they had a diagnosis, something broke, they didn't repair well. All of that. Is true. And I can get them motivated for a little while. And then we have the long game. And you look at that story with a hundred days of sardines. Okay, that's two years into her journey where she finally says, Okay, there's this demon that keeps coming about, and I keep falling off for all the wrong re you know, all the reasons everybody else does.

1:31:03 And so she commits to this hundred days. And what happens is a whole bunch of things go right, her hormones go up. Mm. And she was has an amazing story. But most people are not gonna do that.

1:31:13 So in my practice, I do say that these The smallest dos of these hormones. I'll help you when you're struggling. I want you in a ketogenic state before we we begin. I can use much less that hormone and then you have ownership of this because if I come in and do all of the work again. That's like every other thing I've been doing for the last twenty years.

1:31:33 Here's your symptom, here's my diagnosis, here's the prescription. And I need it to be you that succeeds here. I'll lift you a little bit. So what do you Is there any tricks to get someone to be motivated? Is there any do you have to focus them on their why? Exactly right. You're right. Uh that

1:31:49 That first trick is Get out of crisis mode. Okay, the crisis is what brings them in, but to stay the course. You have to get to a very serious moment where you say, What What motivates me.

1:32:01 What at the deepest heart am I most insecure about that I am gonna do when all else fails, w when everybody else gives up. I'm gonna find something that I'm this little farm kid from the middle of nowhere who was You know, third grade stinky girl like I was a farm kid, I was a hog farmer's daughter. I wasn't the smart one, I wasn't the you know the best one. I'm gonna carry that insecurity with me until the day I die.

1:32:24 What has that done? It makes me work really hard when everybody else gives up. Now finding that For them. en and using that using that harness to say your biggest failure Your biggest insecurity can be your power.

1:32:41 By reframing it. That why is we work on that every time we do that twenty one day. Jane? She did that four times before she really got to the Core center. Why do you keep doing this? That's why people stay motivated.

1:32:56 It's a true it's a truth serum. All I had to do was brain dump. Imagine if you had Someone with you at all times that can take the ideas you have in your head, synthesize them with AI to make them sound better and more grammatically correct, and write them down for you. This is exactly what Whisperflow is in my life. It is this thought partner that helps me explain what I want to say. And it now means that on the go, when I'm alone in my office, when I'm out and about. I can respond to emails and Slack messages and WhatsApp and everything across all of my devices just by speaking. I love this tour. And I started talking about this in my behind the scenes channel a couple of months back, and then the founder reached out to me and said,

1:33:34 We're seeing a lot of people come to our tool because of you. So we'd love to be a sponsor. We'd love you to be an investor in a company. And so I signed up for both of those offers, and I'm now an investor and a huge partner in a company called Whisperflow. You have to check it out. Whisperflow is four times faster than typing. So if you want to give it a try, head over to Whisperflow.ai slash. DOAC to get started for free. And you can find that link. To Whisperflow in the description below. Have you ever heard about this before? This thing I'm holding in my hands now. This is called KetoneIQ. Their website is ketone.com. You've heard me on this podcast talking about the fact that I stay.

1:34:09 much of the year in a ketogenic state, which is a highly restricted diet. And the reason I do that is plentyfold. One of them is I spend hours and hours talking to people for a living. So I want to make sure my brain is firing in an optimal way. And the other reason that I do the ketogenic diet is because I just feel better. So when I discovered this, which is what they call an exogenous ketone product, where you can drink it. And it increases your blood's ketone levels. I was blown away. I contacted them, I met them, I invested. Extremely heavily into their company, and I've become a co owner of the company accordingly, and they sponsor this show now. So if you want to try this out for yourself,

1:34:46 I recommend you try it. Just visit ketone.com slash Steven and you'll get thirty percent off your first subscription order. You'll also get a free gift with your second shipment. That's ketone.com slash Steven. I was reading about what happened to you in two thousand eleven, two thousand ten, two thousand eleven, when you reach what you re you refer to as your breaking point. Corporate medicine. Yeah. And you had some issues because you were, I think, helping some people who Wah

1:35:15 Homeless? Yep. What what do what do I need to know about that and how has that shaped you? Corporate medicine has lots of flaws. And you get tired of answering the same question over and over and over again.

1:35:26 So you put some stuff up on YouTube and you start to say, Here's the education I wish I could give you. Uh and this starts to work. But that's not the that's not the path if you're into corporate medicine. You're gonna ruffle feathers, you're gonna tick people off. Well I left corporate medicine. Start on my own thing.

1:35:44 And I'm living out a two year non compete. Do you know what that means? That you can't do medicine for two years? In that same market where they recruited me and they had advertised for me. Okay. Okay, so you can't compete with what we just

1:35:58 put money into for two years. And they said you can see the homeless. You can see Medicaid. Medicaid being the like government funded medic medicine programme. Low income. So I said they don't know me very well. Those are just as much my people as anybody else. I'm taking care of some native Americans. They were the ones in the shelter. They're the ones with the low income.

1:36:16 And Those teenagers were overweight. And they were eating kitty litter. They were eating toilet paper. Their iron was

1:36:26 So low the machine couldn't measure it. So they're super malnourished. I started doing what I would do if you had all the money in the world. I took care of these patients. I give them IV iron.

1:36:37 Which was expensive. It caused a ruckus. I got put on the radar of somebody that Did not like that. So this is a budget. The whole state gets a budget for how much you're gonna spend on each patient. Yeah. I mean by expense it was like three hundred and fifty bucks.

1:36:50 Per person. That's not that expensive. But it was And nobody else was doing it. And I got a sticky note inside an envelope. From the state capital. Stop doing catalog medicine.

1:37:01 Yeah. So you you were sued eventually? Oh, they they call it Medicaid fraud. Okay. They thought I was wasting Medicare's numbers because I was giving Ivy Iron.

1:37:12 And I said, No, I didn't bill for it. Bill for it, I paid for it. And when I paid for the medicine for these Impoverished. patients they said well that's Medicaid fraud.

1:37:23 So The government tried to sue me for that and they lost. But now they're ticked off. They've brought me to court and they lost. And

1:37:32 What happened next is a lot worse. I don't know if you want to hear the you want me to go there? Okay. So When you are being investigated for Medicaid fraud, all income stops. Yeah.

1:37:45 Yeah, so I have to come home to my husband and say I just can't s I can't Give in. I think we need to fight this. He said, Okay.

1:37:56 He he God bless him, he said, Okay, let's fight it. You ever tried to fight the government? It's very expensive. So they hold off you

1:38:05 When you're under a Medicaid and fraud fr fra fraud investigation, you get no paychecks. So we have no paychecks to pay payroll, to to pay house payments, to do anything for about Nine and a half months actually lasts longer than that. During that time We started doing things like We sold the lake cabin.

1:38:21 We sold the boats. We sold the extra car. We sold our own house. We moved into a Donated R V.

1:38:29 You moved into a car. RV, yep. In South Dakota where there's fifty below zero weather. With three little kids. We actually

1:38:39 Yeah. We took our wedding rings in for the last paycheck. I I just can't give in. And then I won.

1:38:49 Okay, so Medicaid fraud wasn't there. But in the midst of that, I said I this was when Obamacare was really happening. And I got asked to run for US Senate.

1:38:59 There's only a hundred of those in the country. I run for US Senate and I did really good. I raised Insane amounts of money.

1:39:10 Saying I'm a doctor that serves the poor. I am a physician that runs her own company. Uh I think I am a great voice to send to Washington, DC, to make policy about patients. And care.

1:39:25 As opposed to To the other opponents. With that same attorney general? His best buddy was running against me. And when I am in a mission trip.

1:39:35 Uh in the Philippines. That has nothing to do with it, but I was on a mission trip in the Philippines And um I left a petition behind. I don't know how you do it in London, but a petition means if you're gonna run for office, you gotta get some people saying it they believe in you. So we needed two thousand signatures.

1:39:53 And we got six thousand signatures. We submitted them to the state. We think there's no problem. But then the quarterly earnings come back for a campaign raising and my opponent Had about Seventy donors.

1:40:06 At about ten thousand dollars A pop. And we had something like seven hundred and Forty Thousand dollars.

1:40:14 I put my earnings in. And they were seven hundred and eighty thousand dollars. So I outraised him. You have to report. To the government whenever somebody gives you more than two hundred dollars.

1:40:25 So his donors are right there on the list. My list is empty. Because the average size of the donation was forty five dollars. And they know They can't win with that.

1:40:37 I have a grassroots behind me. Um That's when the black cars started. Showing up in my life. It sounds like I've got a tinfoil hat, but it was real. The black one?

1:40:48 The state card started to show up outside my house. They started to say find something on her. And I am the first person in the history of the United States of America. To be investigated for Not witnessing a signature on those petitions.

1:41:05 Okay, so there were these petitions you had to get two thousand of them signed and you had to w witness them so you had to be there when they were signed by people. Well that's what it says and uh you're right, it says I bear witness uh so As I'm I left them in my clinic, my staff signed it.

1:41:22 The Preachers in my My clinic signed it. And those signatures were collected while I was in the Philippines. And so you signed to witness them when you were back from the Philippines. Right. So I didn't witness them.

1:41:34 I just vouched that That's my sister. That's the preacher. I know who these people are. And so they charged you for they realize that you were in the Philippines at the time, so you couldn't have witnessed them based on the dates or something. Yep. And then

1:41:47 They arrested you? Twel twelve felonies. And Twenty four years in prison. That's what they charged you for, or that's what

1:41:59 They charge me with twelve. Six counts for each of the six petitions. Six uh so it's twelve. There's six mistakes, but each mistake counts for two felonies. I mean if you're gonna make a mistake There's one felony. When you're trying to Make a statement.

1:42:16 There's twelve news. And you're the first one in the history of the United States of America ever have this charge, let alone brought to trial. And then found guilty. The trial didn't happen in my state. Town it happened in.

1:42:31 The state capital. Uh Everybody knew that attorney general. Everybody knew the opponent. So they they tried to get you to serve twenty four years in prison. Yeah. They sentenced me to twenty four in prison. They sentenced you to My kids are sitting behind me. I'm you are guilty of twelonies and twenty four years in prison.

1:42:51 And then he says, but the stack of papers in front of me Might be the biggest He'd been a judge for twenty some years. And I had patients who had written in saying, This is the best doctor I've ever seen. I didn't ask them to write that.

1:43:04 Sent them in. That moment when you hear that you're gonna be in prison for twenty four months. Twenty four years. Oh God, it is the lowest moment of my life. Yeah.

1:43:14 I mean I do not Like that the That that story cost the state of South Dakota any money. But I also don't like that when you oppose

1:43:25 The the political Giants. And you stand there with all of the right intentions. That if they need to find something on you, they will. Six petitions.

1:43:39 And we had A thousand extra signatures. There was nothing this was a nothing burger. But it was enough. And that attorney general.

1:43:48 Said Prosecute her to the fullest extent. And I'm not a martyr. I do things that aren't right, and if there was a mistake that I made I I would take full ownership and to that judge I made I took full ownership That

1:44:04 The attorney general was He won. I got sentenced. But you didn't have to serve the twenty four years. He said I'll probate that. I will suspend that with um the highest number of service hours ever in the state of South Dakota. It was five hundred community service hours.

1:44:22 Serving the poorest patients in the state. Well he said those words, I thought. Oh my God, you don't know who I am. That's what I've been doing. I was already working in Pine Ridge. How do you how do you feel about all of this? I mean I I think of it as a test.

1:44:36 It was a test of I mean most marriages aren't gonna make it through that. You've got kids they'll end up in rehab with that much stress. And I didn't want that life. I didn't want that to be my

1:44:50 Ending. I framed it differently. I said, All right, God, you're testing me. You're testing to say can I be Can I stay true to who it is? That

1:44:59 You've called me to be. That our marriage was incredibly Uh

1:45:07 That's a lot of pressure. I mean, I was the number one news story in the whole damn state for three years running by a mile. I can't go anywhere without That's her, that's her. My parents were ashamed.

1:45:20 My kids would say this is the woman that takes me to Haiti and She is mother frickin' Teresa. And now she's on the front page of a newspaper as a twelve time felon. And your teachers at school. Say.

1:45:33 Write about your mom again in the newspaper. Oh It should have been crushed me. But it didn't.

1:45:44 When did your life begin to turn upwards from that point onwards? When was the the moment where Things were Well the first thing is we appealed that to the Supreme Court. That's where the big legal bills come from.

1:45:57 Okay, you're fighting an attorney general, that's where And the Supreme Court said that that attorney general abused his power. For at least six of'em. I'll erase all these because of the work you've done.

1:46:10 So the twelve felonies went away. All of them. Yeah. I think on the edge of that.

1:46:16 Story. Um I work to resurrect people's health back too. A place where they they get their best life. And yes, ketones are a really big part of that. But as you look at

1:46:28 The relationships you've got around your life. Take the core ones and nurture them to a place where Uh Your best life comes out of those relationships. Find the purpose that you've been designed for.

1:46:41 And take those relationship with you as you Seek that. I I know that's what happened to me. I cared about the ones on the inner circle and I had a one. track of this is what I'm designed to do.

1:46:54 We have a closing tradition where the last guest leaves a question for the next, and a question left for you. Is do you have a daily practice? To find deep inner peace. When you are emotionally triggered. And if so.

1:47:08 Please share it with the audience. Yeah, I have a uh devotion that I do every morning. But um That centers me, keeps me In line with my faith.

1:47:21 And it's not That you do it on the bad days. It's that you've got The foundation for doing it on the good days. Mm.

1:47:28 Yeah. Generation. Uh a daily devotion like upper room is a It's a spiritual devotion for My church. Yeah, it's a prayer.

1:47:40 And how does that sound? Yeah, the it's uh usually a scripture and then it's a prayer that has been sh Yeah, paired with that scripture. And again, it's easy to not do it routinely. But when you practice it on the good days.

1:47:54 It's W on those Really tough days. And sometimes you forget you're not the first person to run through these problems. But there are

1:48:04 thousands of generations that have taught you how to do life and get through those hard places. And I'm gonna use their rules. I'm gonna follow what

1:48:15 That Scripture says. And lead for my best life. Doctor Boss, thank you. Very good. We are done. Yeah, I really think I really appreciate so much about you. I appreciate your personality.

1:48:28 Well, I'm incredibly engaging. But I also just um I appreciate that you've taken the time to make so much content over on your YouTube channel, which I'm gonna link on screen and below now. um to sort of demystify and break down some of these really complicated subjects that people struggle with and they're looking for someone who they can trust who has a bit of personality. Um you can communicate some of these very complicated things to them. And on on your channel, you talk about everything from the ketogenic diet to many things we talked about today to the creatine stuff to

1:48:57 Cancer more broadly, this idea of autophagy and fasting, um, and lots of other things. I mean everything we've talked about today and much, much, much more. So I highly recommend people go and check your channel out. If they would like to learn more, it will be linked. Below. And um you've written some wonderful books. Um Some of them that we've referenced, we've got the key to continuum, which I'm gonna link below as well. Um this wonderful book called Any Way You Can, A Beginner's Guide to Keetones for Life, which um

1:49:23 Talks a lot about Rose and has some wonderful photos of Rose. In that but And we have the Keto Continuum Workbook, which is a much more practical Um hand with the other one and it's what I give my patients in The clinic'cause they gotta go through that workbook. I think a lot of people are looking for exactly that. They're looking for

1:49:40 Something that they can follow step by step, which gives them a framework for progress and I guess in in a way holds them accountable, which is exactly what the workbook does. Thank you so much. You're you're you're helping millions of people. You've had a fucking rough ride site. Twelve felonies and twenty four years in prisoners for for something as as little as what you did, I think is is bizarre. Quite frankly, but You know, it's in i a story of inspiration that it didn't hold you back and you've risen like a Phoenix and created so much incredible work there for that's benefit so many. So please do keep going. God bless you. Thanks for having me here. I'm really excited to be on your show. Thank you so much, Doctor Poss. This is something that I've made for you. I've realized that the drivers here audience are strivers, whether it's in business or health. We all have big goals that we want to accomplish. And one of the things I've learned is that when you aim at the big, big, big goal, it can feel incredibly

1:50:32 psychologically uncomfortable because it's kinda like being stood at the foot of Mount Everest and looking upwards. The way to accomplish your goals is by breaking them down into tiny small steps. And we call this in our team the one percent. And actually, this philosophy is highly responsible for much of our success here. So what we've done so that you at home can accomplish any big goal that you have is we've made these One percent diaries. And we released these last year and they all sold out. So I asked my team over and over again to bring the diaries back, but also to introduce some new colours and to make some minor tweaks to the diary. So now we have a better range for you. So if you have a big goal in mind. And you need a framework and a process and some motivation, then I highly recommend you get one of these diaries before they all sell out once again. And you can get yours now at thediary.com where you can get twenty percent off our Black Friday bundle. And if you want the link, the link is in the description below.

1:51:27 Uh

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